NMN Supplements: Powder, Capsules, and High-Dose Options

Compare RevGenetics NMN formats to find your optimal NAD+ strategy. Sublingual powder for speed, NADShield capsules for protection, or 1000mg for clinical protocols.

30 MIN
Rapid Absorption
99%
Pure NMN
38%
NAD+ Increase
SLC12A8
Transporter Tech

Choosing the Right NMN Supplement Format

Nicotinamide Mononucleotide (NMN) is a direct precursor to NAD+ (nicotinamide adenine dinucleotide), the essential coenzyme required for cellular energy production, DNA repair, and sirtuin activation. As NAD+ levels decline with age, supplementation with NMN has emerged as a primary strategy for supporting healthy aging at the cellular level.

RevGenetics offers three distinct NMN formats, each engineered for specific user profiles and goals. The key differentiators are delivery method, dose per serving, absorption speed, and protective technologies. Understanding these differences allows you to select the product that matches your lifestyle and objectives.

Sublingual NMN Powder delivers NMN directly through the tissues under the tongue, bypassing the digestive system entirely. This method engages the SLC12A8 transporter protein within 10 to 15 minutes, making it the fastest option available. The 25-gram container provides 147 servings, offering the lowest cost per milligram for users comfortable with measuring and sublingual administration.

NADShield Capsules combine a moderate 50mg NMN dose with NNMT inhibitor technology. NNMT (nicotinamide N-methyltransferase) is an enzyme that degrades NAD+ precursors before they can be utilized. By including natural NNMT inhibitors like vanillin, NADShield protects your NAD+ investment. This formula also includes resveratrol for sirtuin activation and probiotics for gut health. Enteric coating ensures the capsule reaches the small intestine intact, with absorption occurring within 30 minutes.

High-Dose NMN 1000mg capsules match the dosing used in peer-reviewed clinical trials demonstrating NAD+ increases. The enteric coating provides 6.8x improved dissolution compared to standard gelatin capsules (USP 711 testing). This format is designed for experienced users following clinical protocols or those who want maximum NAD+ support in a single daily capsule.

All RevGenetics NMN products share core quality standards: 99% purity, third-party testing, cGMP manufacturing, and 24-month stability verification. The primary question is which delivery method and dose aligns with your goals. The comparison matrix below provides a direct side-by-side analysis to support your decision.

Anthony Loera, Founder and CEO of RevGenetics

Anthony Loera, Founder & CEO

19+ years formulating longevity supplements | Pioneer in NMN transporter technology

Last Updated: January 7, 2026

NMN Supplement Comparison Matrix

Side-by-side analysis to match product to your goals

Feature Advanced NAD Powder NADShield Capsules NMN 1000mg
NMN per Serving 170mg 50mg + protection 1000mg
Total Servings 147 servings 60 capsules 30 capsules
Delivery Method Sublingual (under tongue) Enteric capsule Enteric capsule
Absorption Speed 10-15 minutes 30 minutes 30 minutes
NNMT Inhibitor No Yes (NADShield) No
Additional Ingredients None (pure NMN) Resveratrol, Probiotics None (pure NMN)
Acid Protection N/A (bypasses stomach) Enteric coated Enteric coated (6.8x dissolution)
Price $80.00 $19.99 $40.00
Cost per mg NMN $0.0032/mg (best value) $0.0067/mg $0.0013/mg
Best For Biohackers seeking speed and value Older adults, beginners, those with high NNMT Clinical protocol users, high-dose seekers

Shop NMN Supplements

FASTEST ABSORPTION Advanced NAD Powder 25g for sublingual absorption

Advanced NAD Powder (25g)

$80.00
  • 99% pure NMN, 170mg per serving
  • 147 servings (best value per mg)
  • Sublingual absorption in 10-15 minutes
  • SLC12A8 transporter technology
  • 24-month stability verified
View Product
NNMT PROTECTION Advanced NAD Capsules with NADShield NNMT inhibitor

Advanced NAD Capsules with NADShield

$19.99
  • 50mg NMN plus NNMT inhibitor
  • NADShield prevents NAD+ breakdown
  • Includes resveratrol and probiotics
  • Enteric-coated, 30-minute absorption
  • 60 capsules per bottle
View Product
CLINICAL DOSE Advanced NMN 1000mg high potency capsules

Advanced NMN 1000mg

$40.00
  • 1000mg NMN per capsule
  • Matches clinical trial dosing
  • Enteric-coated (6.8x dissolution)
  • 30-minute absorption
  • 30 capsules per bottle
View Product

Frequently Asked Questions

What is the difference between NMN powder and capsules?

NMN powder is taken sublingually (under the tongue) for fastest absorption in 10 to 15 minutes, bypassing the digestive system. Capsules use enteric coating to protect NMN through stomach acid, absorbing in about 30 minutes. Powder offers more servings per dollar; capsules offer convenience and precise dosing.

Which NMN supplement is best for beginners?

Advanced NAD Capsules with NADShield are ideal for beginners. The 50mg dose is conservative, the NNMT inhibitor prevents NAD+ breakdown, and the capsule format requires no measuring. Included resveratrol and probiotics provide additional support.

Who should use high-dose NMN 1000mg?

The 1000mg NMN is designed for clinical protocol users who want to match dosing used in peer-reviewed research studies. It is appropriate for experienced users who have established tolerance with lower doses and want maximum NAD+ support.

What is NADShield and why does it matter?

NADShield is RevGenetics' NNMT inhibitor technology using natural compounds like vanillin. NNMT is an enzyme that breaks down NAD+ precursors before they can be used. By inhibiting NNMT, NADShield preserves your NAD+ investment, especially valuable for older adults with higher NNMT activity.

How fast does NMN absorb?

Sublingual powder absorbs in 10 to 15 minutes by bypassing digestion and entering the bloodstream directly. Enteric-coated capsules absorb in approximately 30 minutes after dissolving in the small intestine. Both methods utilize the SLC12A8 transporter protein.

Can I combine different NMN products?

Yes. Many customers use NADShield Capsules daily for NNMT protection and add Powder or High-Dose NMN on days requiring extra support. The products use the same transporter pathway and can be combined within recommended daily limits.

📚 ESSENTIAL READING

NMN vs NAD+ vs Niacin vs Niacinamide: What is the Difference?

All four are vitamin B3 compounds, but they have dramatically different bioavailability, side effects, and cellular benefits. Understanding these differences is crucial for choosing the right NAD+ booster.

Read the Complete Vitamin B3 Guide

Important Health Information

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

Quality Assurance:

  • 99% pure pharmaceutical grade NMN
  • Enteric-coated delivery systems
  • Third-party tested for purity
  • cGMP certified facilities
  • 24-month stability verification
  • Ships to 50+ countries