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RevGenetics Advanced NAD & NADshield: NNMT Inhibitor for NAD+ Protection and Longevity By RevGenetics AdvancedNAD300-2 Member Products,All Products

Advanced NAD & NADshield: NNMT Inhibitor for NAD+ Protection and Longevity By RevGenetics

Regular price$40.00
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  • Feel Vibrant Again: Boosts your energy in just 30 minutes – perfect for busy professionals and active adults.
  • Support Longevity: NADShield™ technology protects NAD levels, helping you age gracefully.
  • Optimize Cellular Health: Enhances mitochondrial function, backed by 10+ years of research.

Advanced NAD & NADshield: NNMT Inhibitor for NAD+ Protection and Longevity By RevGenetics

  • Feel Vibrant Again: Boosts your energy in just 30 minutes – perfect for busy professionals and active adults.
  • Support Longevity: NADShield™ technology protects NAD levels, helping you age gracefully.
  • Optimize Cellular Health: Enhances mitochondrial function, backed by 10+ years of research.

NAD Supplement: Advanced NAD with NADShield NNMT Inhibitor for Revolutionary Cellular Protection

Advanced NAD with NADShield supplement NNMT inhibitor for enhanced NAD protection and cellular energy

Discover the breakthrough in NAD supplement technology with Advanced NAD featuring NADShield, the first formulation to combine rapid-absorption NAD precursors with revolutionary NNMT inhibitor protection. This innovative approach addresses a critical limitation in NAD supplementation: the premature breakdown of NAD by the NNMT enzyme, ensuring your body can actually utilize the NAD precursors you consume for maximum cellular energy and longevity benefits.

Revolutionary Fast Absorption

30 minutes

Rapid NAD delivery vs. 8+ hours
with traditional supplements

Why NAD Supplement Protection Changes Everything

Traditional NAD supplements face a hidden challenge that most people don't know about: the NNMT enzyme actively breaks down NAD precursors before they can be converted into usable NAD+. This enzymatic degradation explains why many people don't experience the expected benefits from standard NAD supplementation, regardless of dosage.

Advanced NAD with NADShield solves this fundamental problem by incorporating natural NNMT inhibitors that protect your NAD investment. The result is superior bioavailability, enhanced cellular energy production, and more pronounced anti-aging benefits from every dose.

NNMT Protection Technology: NADShield contains concentrated natural ingredients including 4-Hydroxy-3-methoxybenzaldehyde from vanilla beans, scientifically shown to inhibit NNMT enzyme activity. This protection ensures NAD precursors reach their cellular targets intact, maximizing therapeutic benefits.

The Science Behind NNMT Inhibition and NAD Supplements

NNMT (Nicotinamide N-methyltransferase) represents one of the most significant but overlooked barriers to effective NAD supplement benefits. This enzyme systematically breaks down NAD precursors, reducing the amount available for conversion to active NAD+ in your cells.

Recent breakthrough research in mice demonstrated that NNMT inhibition dramatically enhanced endurance and metabolic health. The study showed mice treated with NNMT inhibitors experienced substantial increases in running capacity over 8 weeks, highlighting the profound impact of protecting NAD from enzymatic breakdown.

NNMT inhibitor study results showing increased endurance in mice with NAD supplement protection

Groundbreaking Research Results

The mouse study revealed that NNMT inhibition led to dramatic improvements in physical performance over 8 weeks. Inspired by these findings, RevGenetics formulated NADShield using concentrated natural NNMT inhibitors to provide similar protective benefits for human NAD supplementation.

How NADShield Protects Your NAD Investment

NADShield works by creating a protective barrier around NAD precursors, allowing them to reach cellular targets before NNMT can break them down. This protection mechanism ensures that more of your NAD supplement intake actually contributes to cellular energy production rather than being wasted through enzymatic degradation.

The result is enhanced NAD+ levels, improved mitochondrial function, and more pronounced benefits for cellular health, energy production, and healthy aging processes. Users often notice improved energy levels, better recovery, and enhanced overall vitality when NAD precursors are properly protected.

Enhanced NAD Protection

NNMT inhibition prevents premature breakdown of NAD precursors, ensuring maximum utilization for cellular energy.

Superior Bioavailability

30-minute absorption delivers NAD precursors rapidly while NADShield provides ongoing protection.

Comprehensive Cellular Support

Combines NAD optimization with antioxidants and probiotics for holistic cellular health enhancement.

Synergistic Longevity Benefits

Works harmoniously with resveratrol and other longevity compounds without sirtuin downregulation.

Advanced Ingredient Profile for Maximum NAD Support

Revolutionary NADShield Formula

Each serving of Advanced NAD with NADShield delivers 50mg of premium NAD precursor plus a comprehensive blend of protective and supportive compounds:

Core NAD Protection:

  • 4-Hydroxy-3-methoxybenzaldehyde: Natural NNMT inhibitor extracted from vanilla beans, scientifically validated for protecting NAD from enzymatic breakdown
  • Advanced NAD Precursor: Rapid-absorption formula that reaches cells in 30 minutes for immediate energy support

Synergistic Support Compounds:

  • Trans-Resveratrol: Potent antioxidant that supports cardiovascular health and combats oxidative stress for healthy aging
  • Bifidobacterium Infantis: Beneficial probiotic enhancing gut health and nutrient absorption for optimal supplement utilization
  • Lactobacillus Salivarius: Probiotic supporting balanced gut microbiome and improved uptake of critical nutrients

Why This Combination Works

The Advanced NAD with NADShield formulation addresses multiple aspects of NAD optimization simultaneously. While the NAD precursor provides raw materials for cellular energy production, NADShield ensures these materials reach their targets intact. The addition of resveratrol provides antioxidant support, while probiotics optimize the gut environment for enhanced absorption.

This comprehensive approach ensures that your NAD supplement investment delivers maximum benefits across multiple pathways of cellular health and longevity support.

NAD Supplement Benefits and Applications

Comprehensive Health Benefits

  • Protects NAD from premature enzymatic breakdown
  • Boosts NAD+ levels naturally and efficiently
  • Supports cellular health and repair mechanisms
  • Enhances mitochondrial function and energy production
  • Promotes healthy aging and longevity pathways
  • Provides antioxidant protection against oxidative stress
  • Includes probiotics for improved gut health and absorption
  • Works synergistically with resveratrol and other longevity compounds
  • Does not downregulate sirtuins like some NAD precursors
  • Fast 30-minute absorption for rapid cellular delivery

Ideal Users for Advanced NAD with NADShield

This revolutionary NAD supplement proves invaluable for health-conscious individuals seeking to optimize their cellular energy and longevity. Whether you're an athlete pursuing peak performance, a biohacker exploring cutting-edge longevity protocols, or a health enthusiast committed to healthy aging, NADShield offers an innovative approach to maximizing NAD benefits.

The formulation particularly benefits those who have tried traditional NAD supplements without experiencing expected results, as the NNMT protection often resolves the underlying absorption and utilization challenges that limit conventional approaches.

Important Health Information: Advanced NAD with NADShield is designed for overall health and wellness support as a dietary supplement. While this product provides innovative NAD protection technology, we make no medical claims about its ability to diagnose, treat, cure, or prevent any disease. Always consult your healthcare provider before starting any new supplement regimen.

Experience Advanced NAD Protection

Maximizing Your NAD Supplement Strategy

The revolutionary NNMT inhibition technology in Advanced NAD with NADShield opens new possibilities for optimizing NAD supplement strategies and achieving superior results from longevity protocols. Understanding how to integrate this technology effectively ensures maximum benefits from your cellular health investment.

Enhanced Compatibility with Existing Supplements

Advanced NAD with NADShield demonstrates exceptional compatibility with existing supplement regimens. Unlike some NAD precursors that may interfere with sirtuin activation, this formulation works synergistically with resveratrol and other longevity compounds to provide comprehensive cellular support.

Many users successfully combine Advanced NAD with NADShield alongside their current NMN supplements, creating a multi-layered approach to NAD optimization. The NNMT protection benefits both the included NAD precursor and any additional NAD supplements you may be taking.

Timing and Dosage Optimization

The rapid 30-minute absorption profile of Advanced NAD with NADShield allows for flexible timing based on your individual needs and lifestyle. Some users prefer morning supplementation to support energy levels throughout the day, while others find evening dosing supports cellular repair processes during sleep.

The inclusion of probiotics makes this NAD supplement gentle on the digestive system, allowing for consistent daily use without the gastric upset sometimes associated with high-dose NAD precursors.

Long-Term Cellular Health Strategy

Advanced NAD with NADShield represents a foundational component of comprehensive cellular health and longevity protocols. The NNMT protection technology ensures that your NAD investment provides sustained benefits over time, rather than being limited by enzymatic degradation.

As research continues to reveal new insights into NAD metabolism and cellular aging, formulations like Advanced NAD with NADShield position users at the forefront of evidence-based longevity science. The combination of rapid absorption, enzymatic protection, and synergistic support compounds creates a robust foundation for healthy aging and cellular optimization.

The Future of NAD Supplementation

The integration of NNMT inhibition technology represents a paradigm shift in NAD supplement design. By addressing the fundamental challenge of enzymatic breakdown, Advanced NAD with NADShield points toward a future where NAD supplementation achieves its full therapeutic potential through intelligent formulation and scientific innovation.

FDA Disclaimer: *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Advanced NAD with NADShield is a dietary supplement intended for general health and wellness support only.

Frequently Asked Questions About NAD Supplements with NNMT Protection

What makes Advanced NAD with NADShield different from other NAD supplements?
Advanced NAD with NADShield represents a revolutionary breakthrough in NAD supplement technology as the first formulation to combine rapid 30-minute absorption with comprehensive NNMT inhibitor protection. While traditional NAD supplements lose significant effectiveness due to the NNMT enzyme breaking down NAD precursors before they can be utilized, NADShield's natural inhibitors protect these valuable compounds from premature degradation. This ensures maximum cellular utilization and delivers superior energy, longevity, and cellular health benefits that other supplements simply cannot match.
How does NNMT inhibition improve NAD supplement effectiveness?
NNMT (Nicotinamide N-methyltransferase) is an enzyme that systematically breaks down NAD precursors before they can be converted to usable NAD+ in your cells. This enzymatic breakdown represents a hidden barrier that explains why many people don't experience expected benefits from standard NAD supplements, regardless of dosage. NADShield contains concentrated natural NNMT inhibitors, including 4-Hydroxy-3-methoxybenzaldehyde extracted from vanilla beans, that create a protective barrier around NAD precursors, allowing significantly more to reach their cellular targets for energy production and longevity benefits.
What research supports NNMT inhibition for health benefits?
Groundbreaking research in mice demonstrated that NNMT inhibition dramatically enhances endurance and metabolic health over 8 weeks. The study showed mice treated with NNMT inhibitors experienced substantial improvements in running capacity, highlighting the profound impact of protecting NAD from enzymatic breakdown. These findings inspired RevGenetics to formulate NADShield using concentrated natural NNMT inhibitors to provide similar protective benefits for human NAD supplementation, representing the cutting edge of longevity science.
Can I take Advanced NAD with NADShield alongside other NAD supplements?
Absolutely! Advanced NAD with NADShield is specifically designed to work synergistically with other NAD supplements like NMN capsules. The revolutionary NNMT protection technology benefits both the included NAD precursor and any additional NAD supplements you may be taking, creating a powerful multi-layered approach to NAD optimization. Many users successfully combine this with their existing regimens to achieve enhanced overall benefits and superior cellular energy support.
What ingredients are included in the comprehensive NADShield formula?
Each serving delivers 50mg of premium NAD precursor plus a sophisticated blend of protective and supportive compounds. The core includes 4-Hydroxy-3-methoxybenzaldehyde (a natural NNMT inhibitor extracted from vanilla beans), trans-resveratrol for pot

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


🧬 Research Dosage Converter

Allometric scaling using FDA Km factors to compare doses across species

Human (kg)
Mouse (kg)
Rat (kg)
Dog (kg)
Worm (kg)
Fly (kg)

Equivalent Dosages

Species Equivalent Dose (mg/kg) Total Amount / Day (mg) Method
* Research reference only. Uses FDA Km factors: Human 37, Dog 20, Rat 6, Mouse 3. Estimated Km for Worm 1000, Fly 500. Conversion: DoseB = DoseA × (KmA / KmB). Total mg computed from assumed weights above. © 2025 RevGenetics, LLC. Unauthorized reproduction prohibited (ID: RG-CALC-20250907).