Advanced NAD & NADshield: NNMT Inhibitor for NAD+ Protection and Longevity By RevGenetics
- Feel Vibrant Again: Boosts your energy in just 30 minutes – perfect for busy professionals and active adults.
- Support Longevity: NADShield™ technology protects NAD levels, helping you age gracefully.
- Optimize Cellular Health: Enhances mitochondrial function, backed by 10+ years of research.
NAD Supplement: Advanced NAD with NADShield NNMT Inhibitor for Revolutionary Cellular Protection

Discover the breakthrough in NAD supplement technology with Advanced NAD featuring NADShield, the first formulation to combine rapid-absorption NAD precursors with revolutionary NNMT inhibitor protection. This innovative approach addresses a critical limitation in NAD supplementation: the premature breakdown of NAD by the NNMT enzyme, ensuring your body can actually utilize the NAD precursors you consume for maximum cellular energy and longevity benefits.
Revolutionary Fast Absorption
Rapid NAD delivery vs. 8+ hours
with traditional supplements
Why NAD Supplement Protection Changes Everything
Traditional NAD supplements face a hidden challenge that most people don't know about: the NNMT enzyme actively breaks down NAD precursors before they can be converted into usable NAD+. This enzymatic degradation explains why many people don't experience the expected benefits from standard NAD supplementation, regardless of dosage.
Advanced NAD with NADShield solves this fundamental problem by incorporating natural NNMT inhibitors that protect your NAD investment. The result is superior bioavailability, enhanced cellular energy production, and more pronounced anti-aging benefits from every dose.
NNMT Protection Technology: NADShield contains concentrated natural ingredients including 4-Hydroxy-3-methoxybenzaldehyde from vanilla beans, scientifically shown to inhibit NNMT enzyme activity. This protection ensures NAD precursors reach their cellular targets intact, maximizing therapeutic benefits.
The Science Behind NNMT Inhibition and NAD Supplements
NNMT (Nicotinamide N-methyltransferase) represents one of the most significant but overlooked barriers to effective NAD supplement benefits. This enzyme systematically breaks down NAD precursors, reducing the amount available for conversion to active NAD+ in your cells.
Recent breakthrough research in mice demonstrated that NNMT inhibition dramatically enhanced endurance and metabolic health. The study showed mice treated with NNMT inhibitors experienced substantial increases in running capacity over 8 weeks, highlighting the profound impact of protecting NAD from enzymatic breakdown.

Groundbreaking Research Results
The mouse study revealed that NNMT inhibition led to dramatic improvements in physical performance over 8 weeks. Inspired by these findings, RevGenetics formulated NADShield using concentrated natural NNMT inhibitors to provide similar protective benefits for human NAD supplementation.
How NADShield Protects Your NAD Investment
NADShield works by creating a protective barrier around NAD precursors, allowing them to reach cellular targets before NNMT can break them down. This protection mechanism ensures that more of your NAD supplement intake actually contributes to cellular energy production rather than being wasted through enzymatic degradation.
The result is enhanced NAD+ levels, improved mitochondrial function, and more pronounced benefits for cellular health, energy production, and healthy aging processes. Users often notice improved energy levels, better recovery, and enhanced overall vitality when NAD precursors are properly protected.
Enhanced NAD Protection
NNMT inhibition prevents premature breakdown of NAD precursors, ensuring maximum utilization for cellular energy.
Superior Bioavailability
30-minute absorption delivers NAD precursors rapidly while NADShield provides ongoing protection.
Comprehensive Cellular Support
Combines NAD optimization with antioxidants and probiotics for holistic cellular health enhancement.
Synergistic Longevity Benefits
Works harmoniously with resveratrol and other longevity compounds without sirtuin downregulation.
Advanced Ingredient Profile for Maximum NAD Support
Revolutionary NADShield Formula
Each serving of Advanced NAD with NADShield delivers 50mg of premium NAD precursor plus a comprehensive blend of protective and supportive compounds:
Core NAD Protection:
- 4-Hydroxy-3-methoxybenzaldehyde: Natural NNMT inhibitor extracted from vanilla beans, scientifically validated for protecting NAD from enzymatic breakdown
- Advanced NAD Precursor: Rapid-absorption formula that reaches cells in 30 minutes for immediate energy support
Synergistic Support Compounds:
- Trans-Resveratrol: Potent antioxidant that supports cardiovascular health and combats oxidative stress for healthy aging
- Bifidobacterium Infantis: Beneficial probiotic enhancing gut health and nutrient absorption for optimal supplement utilization
- Lactobacillus Salivarius: Probiotic supporting balanced gut microbiome and improved uptake of critical nutrients
Why This Combination Works
The Advanced NAD with NADShield formulation addresses multiple aspects of NAD optimization simultaneously. While the NAD precursor provides raw materials for cellular energy production, NADShield ensures these materials reach their targets intact. The addition of resveratrol provides antioxidant support, while probiotics optimize the gut environment for enhanced absorption.
This comprehensive approach ensures that your NAD supplement investment delivers maximum benefits across multiple pathways of cellular health and longevity support.
NAD Supplement Benefits and Applications
Comprehensive Health Benefits
- Protects NAD from premature enzymatic breakdown
- Boosts NAD+ levels naturally and efficiently
- Supports cellular health and repair mechanisms
- Enhances mitochondrial function and energy production
- Promotes healthy aging and longevity pathways
- Provides antioxidant protection against oxidative stress
- Includes probiotics for improved gut health and absorption
- Works synergistically with resveratrol and other longevity compounds
- Does not downregulate sirtuins like some NAD precursors
- Fast 30-minute absorption for rapid cellular delivery
Ideal Users for Advanced NAD with NADShield
This revolutionary NAD supplement proves invaluable for health-conscious individuals seeking to optimize their cellular energy and longevity. Whether you're an athlete pursuing peak performance, a biohacker exploring cutting-edge longevity protocols, or a health enthusiast committed to healthy aging, NADShield offers an innovative approach to maximizing NAD benefits.
The formulation particularly benefits those who have tried traditional NAD supplements without experiencing expected results, as the NNMT protection often resolves the underlying absorption and utilization challenges that limit conventional approaches.
Important Health Information: Advanced NAD with NADShield is designed for overall health and wellness support as a dietary supplement. While this product provides innovative NAD protection technology, we make no medical claims about its ability to diagnose, treat, cure, or prevent any disease. Always consult your healthcare provider before starting any new supplement regimen.
Maximizing Your NAD Supplement Strategy
The revolutionary NNMT inhibition technology in Advanced NAD with NADShield opens new possibilities for optimizing NAD supplement strategies and achieving superior results from longevity protocols. Understanding how to integrate this technology effectively ensures maximum benefits from your cellular health investment.
Enhanced Compatibility with Existing Supplements
Advanced NAD with NADShield demonstrates exceptional compatibility with existing supplement regimens. Unlike some NAD precursors that may interfere with sirtuin activation, this formulation works synergistically with resveratrol and other longevity compounds to provide comprehensive cellular support.
Many users successfully combine Advanced NAD with NADShield alongside their current NMN supplements, creating a multi-layered approach to NAD optimization. The NNMT protection benefits both the included NAD precursor and any additional NAD supplements you may be taking.
Timing and Dosage Optimization
The rapid 30-minute absorption profile of Advanced NAD with NADShield allows for flexible timing based on your individual needs and lifestyle. Some users prefer morning supplementation to support energy levels throughout the day, while others find evening dosing supports cellular repair processes during sleep.
The inclusion of probiotics makes this NAD supplement gentle on the digestive system, allowing for consistent daily use without the gastric upset sometimes associated with high-dose NAD precursors.
Long-Term Cellular Health Strategy
Advanced NAD with NADShield represents a foundational component of comprehensive cellular health and longevity protocols. The NNMT protection technology ensures that your NAD investment provides sustained benefits over time, rather than being limited by enzymatic degradation.
As research continues to reveal new insights into NAD metabolism and cellular aging, formulations like Advanced NAD with NADShield position users at the forefront of evidence-based longevity science. The combination of rapid absorption, enzymatic protection, and synergistic support compounds creates a robust foundation for healthy aging and cellular optimization.
The Future of NAD Supplementation
The integration of NNMT inhibition technology represents a paradigm shift in NAD supplement design. By addressing the fundamental challenge of enzymatic breakdown, Advanced NAD with NADShield points toward a future where NAD supplementation achieves its full therapeutic potential through intelligent formulation and scientific innovation.
FDA Disclaimer: *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Advanced NAD with NADShield is a dietary supplement intended for general health and wellness support only.
Frequently Asked Questions About NAD Supplements with NNMT Protection
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
🧬 Research Dosage Converter
Allometric scaling using FDA Km factors to compare doses across species
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