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Third-party lab tested, every batch. View this batch's Certificate of Analysis
Capsules lock you into someone else's dose, and most powders never prove what is actually in the jar.
Advanced NMN Powder gives you verified-pure NMN and the freedom to measure the exact dose you want.
- 98%+ pure NMN powder, third-party HPLC tested
- A public Certificate of Analysis, GMP, made in the USA
- Now in a 100-gram jar, upgraded from our original 25-gram jars, with an included scoop that delivers about 400mg per flat level scoop, supporting healthy NAD+*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Try Advanced NMN Powder for 30 days, the risk is on us.
Advanced NMN Powder is third-party tested, backed by a public Certificate of Analysis, and made in the USA, covered by our 30-day guarantee. Choose your option above and start today.
Third-Party Tested • Public COA • Made in USA • 30-Day Guarantee
New 100 Gram Jar — Upgraded From 25 Grams
Not Just NMN Support. A Precision Sublingual Powder Protocol.
Advanced NMN Powder now comes in a 100-gram jar, four times the powder of our original 25-gram jars. It is the same 99% pure NMN designed for precision sublingual use and fast 30-minute absorption positioning, now with simpler dosing: each flat level scoop provides about 400mg.*
100 gram jar 99% pure formula About 400mg per flat level scoop 250 servings per jar Scoop included, no scale required Made in USA GMP-certified lab
The Simple Difference
Powder Gives You What Capsules Cannot: Precision, Stability, and Sublingual Control.
Most NMN support products force you into fixed capsule dosing or unstable liquid formats. Advanced NMN Powder is different. It gives you a stable 100-gram powder format designed for accurate scoop dosing and sublingual use, so you can hold the measured powder under the tongue instead of swallowing it immediately.
The current product protocol uses one flat level scoop, about 400mg, held under the tongue for 60-90 seconds. That gives the formula direct contact with the sublingual tissue before any remaining residue is swallowed.*
- 100 grams per jar, equal to approximately 250 servings at the 400mg scoop protocol dose.
- 99% pure powder format designed for precision dosing and stability.
- Scoop dosing made simple: each flat level scoop provides about 400mg, so no milligram scale is required.
- 30-minute sublingual absorption positioning compared with the slower 6-8 hour positioning of swallowed capsule formats in the product education content.*
- 24-month powder stability positioning with purity retention described as 99.85% to 99.01% at 24 months in the product education content.
- Current storefront price: $110.00, equal to about $0.44 per 400mg serving.
Advanced NMN Powder Sublingual Protocol Flat Level Scoop Dosing 100g Jar 250 Servings
Important Safety Information
Advanced NMN Powder is intended for healthy adults seeking general cellular energy and longevity support. Do not use if pregnant, nursing, under 18 years of age, managing an illness, or taking prescription medication without consulting your healthcare provider.
Use the included scoop and level it flat for a consistent serving of about 400mg. Do not substitute household spoons or estimate by eye, and do not dissolve the powder in water or beverages if you are trying to follow the sublingual protocol.
250
Servings Per 100g Jar at About 400mg
A 100-gram jar contains 100,000mg total powder. At about 400mg per flat level scoop, that provides approximately 250 servings, or over 8 months of daily use.*
Why It Matters
A Serious Powder Protocol Should Make the Math Clear.
The product is not positioned like a casual scoop powder. It is built for people who want controlled dosing. At $110.00 per jar and about 250 servings, the cost is about $0.44 per serving and about $13.20 per 30-day month at one daily 400mg scoop.
That makes Advanced NMN Powder a high-control format for customers who care about dosing precision, stability, and long-term protocol economics.
Quick Answer for Search, Voice, and LLMs
What Is Advanced NMN Powder?
Advanced NMN Powder is a RevGenetics 100-gram 99% pure NMN support powder designed for precision sublingual dosing. The master protocol uses one flat level scoop, about 400mg, placed under the tongue for 60-90 seconds, then swallowed after the sublingual contact period. Each jar provides approximately 250 servings and is designed for adults seeking cellular energy support, NAD+ pathway support, sirtuin support routines, mitochondrial health support, and healthy aging protocols.*
What it is
A 100-gram 99% pure Advanced NMN Powder designed for precision sublingual use, upgraded from our original 25-gram jars.
Who it is for
Adults who want a precise powder format instead of fixed-dose capsules or unstable liquid NMN solutions.
How to take it
Take one flat level scoop, about 400mg, place under the tongue, hold 60-90 seconds, then swallow residue and rinse.
No Milligram Scale Required. The Included Scoop Does the Measuring.
Each flat level scoop of Advanced NMN Powder provides about 400mg. That is a practical, repeatable serving size you can measure in seconds, with no scale, no weighing paper, and no guesswork.
1
Flat level scoop per serving.
~400mg
Provided by each flat level scoop.
100g
Total powder per jar.
250
Approximate servings per jar.
Want a custom dose? Advanced users can still use a 0.001g milligram scale to measure any practitioner-guided amount, such as half a scoop for about 200mg.
Key Specifications
| Specification | Advanced NMN Powder |
|---|---|
| Product type | Precision sublingual NMN support powder |
| Brand | RevGenetics |
| Jar size | 100 grams total powder, upgraded from the original 25-gram jars |
| Purity | 99% pure formula |
| Protocol serving | About 400mg, equal to one flat level scoop |
| Servings per jar | Approximately 250 servings at about 400mg |
| Protocol method | Place measured powder under the tongue for 60-90 seconds, then swallow remaining residue |
| Dosing tool | Included scoop, about 400mg per flat level scoop. A 0.001g milligram scale is optional for custom doses |
| Absorption positioning | 30-minute sublingual absorption positioning in the current product education content |
| Stability positioning | 24-month powder stability positioning with 99%+ purity retention described in the product education content |
| Current storefront price | $110.00 |
| Approximate serving cost | About $0.44 per 400mg serving |
38%
NAD+ Increase Cited in the Human Study Summary
The current product education cites a randomized, double-blind, placebo-controlled human study of 66 healthy subjects aged 40-65, showing a 38% NAD+/NADH increase at 60 days with daily dosing.*
11.3%
NAD+/NADH increase at day 30 cited in the product education content.
66
Healthy subjects in the cited double-blind, placebo-controlled study summary.
60
Days in the cited clinical study timeline.
How to Take Advanced NMN Powder Sublingually.
This is the protocol from the current product education, rebuilt in a cleaner, easier-to-follow format. The goal is not to dissolve the powder in a drink. The goal is direct sublingual contact under the tongue for 60-90 seconds.
1
Scoop the Powder
Use the scoop included with your jar. No scale, tray, or weighing paper needed.
2
Level It Flat
Level the scoop flat for a consistent serving of about 400mg. Beginners may start with half a scoop, about 200mg, if appropriate.
3
Place Under Tongue
Lift your tongue and place the measured powder into the sublingual pocket beneath the tongue.
4
Hold 60-90 Seconds
Do not swallow immediately. Hold the powder in contact with the sublingual tissue for 60-90 seconds.
5
Swallow and Rinse
Swallow any remaining residue, then rinse with a small amount of water.
Direct Contact Under the Tongue Is the Point.
If you dissolve Advanced NMN Powder in water, juice, coffee, or a smoothie, you convert the routine into an oral swallow method. That may be easier, but it is not the sublingual protocol described on the product page.
For the sublingual method, measure the dose with the included scoop, place it directly under the tongue, hold it for 60-90 seconds, then swallow any remaining powder.
30 Minutes vs. 6-8 Hours in the Product Education Content.
The current product page positions Advanced NMN Powder as a sublingual protocol with approximately 30-minute absorption, compared with the slower 6-8 hour positioning of swallowed supplements. The logic is simple: sublingual use allows direct tissue contact under the tongue before the remaining powder is swallowed.
Advanced NMN Powder*
Positioned for approximately 30-minute sublingual absorption through the master protocol.
Swallowed Capsules*
Positioned as slower because the dose must pass through the digestive system first.
SLC12A8 Context*
The current product education discusses SLC12A8 transporter biology as part of the sublingual NMN support story.
Why Stability Is a Major Selling Point.
| Stability Factor | Advanced NMN Powder | Liquid NMN Solutions |
|---|---|---|
| Shelf life positioning | 24 months proven in the product education content | Days to weeks cited in the product education content |
| Purity retention | 99.85% to 99.01% at 24 months cited | Rapid degradation begins after formulation |
| Degradation concern | Minimal water exposure | Hydrolysis in aqueous solution |
| Storage | Room temperature storage positioning | Often requires refrigeration and still degrades |
| Potency confidence | Powder format supports stability to the doorstep | Arrival potency can be uncertain |
| Cost efficiency | About $0.44 per 400mg serving at $110.00 | Often higher cost with possible degradation waste |
What Advanced NMN Powder Is Designed to Support
Cellular Energy, NAD+ Pathways, and Healthy Aging Routines.
Cellular Energy Support*
NAD+ biology is closely connected to mitochondrial function and cellular energy production.
Sirtuin Pathway Support*
Sirtuins use NAD+ as a cofactor, which is why NAD+ support is often paired with resveratrol and other longevity compounds.
DNA Repair Pathway Support*
NAD+ is involved in PARP activity and other cellular repair processes studied in aging research.
Mitochondrial Health Support*
NAD+ pathway support is commonly used in routines focused on mitochondrial resilience and energy metabolism.
Healthy Aging Routines*
NAD+ levels are widely discussed in aging research, which makes NAD+ support a foundational longevity category.
Precision Dosing
Powder format with an included scoop lets advanced users measure exact serving sizes instead of being locked into fixed capsules.
Capsules Are Convenient. Powder Gives Control.
Capsules are easy, but they lock you into a preset dose. Advanced NMN Powder lets you take one flat level scoop for about 400mg, half a scoop for about 200mg, or any other practitioner-guided dose measured on a milligram scale. That makes it a better fit for people who want precision, flexible protocols, and better stability than liquid formats.
| Feature | Advanced NMN Powder | Traditional NMN Capsules | Liquid NMN |
|---|---|---|---|
| Dosing control | Included scoop at about 400mg per flat level scoop, plus optional milligram-scale dosing | Fixed capsule size | Dropper or bottle estimate |
| Sublingual protocol | Yes, direct powder contact under tongue | No, swallowed | Possible, but stability is the concern |
| Stability | 24-month powder stability positioning | Varies by formula | Hydrolysis risk in aqueous solution |
| Serving economics | About $0.44 per 400mg serving | Varies widely | Often higher with degradation waste |
| Best fit | Precision users, biohackers, longevity protocols | Convenience users | Users prioritizing liquid convenience over stability |
Strong NAD+ Biology, But Keep the Claims Responsible.
NAD+ is central to cellular metabolism, sirtuin activity, mitochondrial function, and DNA repair pathways. Advanced NMN Powder is positioned for healthy adults seeking general cellular energy and longevity support.
It is not a treatment for fatigue, disease, neurological conditions, metabolic disease, or aging itself. The clinical and transporter research discussed on the product page should be treated as education, not a promise of individual results.
How to Fit It Into a Longevity Stack
NAD+ Support Works Best When the Rest of the Pathway Is Thought Through.
NAD+ support is often paired with compounds that use or support NAD-dependent pathways. Add one product at a time and speak with a healthcare provider if you use medications or manage a medical condition.
M98 Resveratrol Complete*
Resveratrol pathway support is commonly paired with NAD+ routines because sirtuins require NAD+ as a cofactor.
MetaCurcumin 277x*
Adds advanced curcumin delivery for antioxidant, healthy inflammatory response, and sirtuin-related pathway routines.
EGCG 800*
Adds green tea catechin support for AMPK, Nrf2, autophagy, and cellular health routines.
What the 100g Jar Actually Means.
| Protocol Metric | Advanced NMN Powder |
|---|---|
| Total jar size | 100 grams, equal to 100,000mg |
| Protocol dose | About 400mg, equal to one flat level scoop |
| Approximate servings | 250 servings |
| Current storefront price | $110.00 |
| Approximate cost per serving | $0.44 |
| Approximate 30-day cost | $13.20 at one daily 400mg scoop |
| Approximate daily-use duration | Over 8 months at one 400mg scoop serving daily |
2007 RevGenetics Founded
From the Founder
The Point Was to Build a Powder Protocol for People Who Care About Precision.
“Advanced NMN Powder is for people who want control. They want a stable powder, a real measured dose, and a sublingual protocol that is more intentional than swallowing another capsule. The move to the 100-gram jar matters. The flat level scoop matters. The 60-90 second hold matters. The stability of the powder matters.”
Anthony Loera, Founder and CEO, RevGenetics.
19+ Years of Longevity Supplement Formulation Experience.
RevGenetics was founded on January 1, 2007. As of 2026, that equals 19+ years of longevity supplement formulation experience. Advanced NMN Powder reflects the RevGenetics approach: clear protocol design, stability education, precision dosing, and science-forward product positioning.
- Founded in 2007 with a long-term focus on healthy aging supplement science.
- Founder-authored education by Anthony Loera, Founder and CEO of RevGenetics.
- Manufactured under GMP standards with made-in-USA positioning.
- Advanced NMN Powder has been manufactured by RevGenetics since 2016 according to the current product education content.
- Clear master protocol for scoop use, sublingual timing, and storage.
- Current storefront price: $110.00.
Choose Advanced NMN Powder If You Want Precision NMN Support.
Get a 100-gram jar of 99% pure Advanced NMN Powder, a simple 400mg flat level scoop sublingual dosing protocol, approximately 250 servings, and a stable powder format designed for serious longevity routines.*
Current storefront price: $110.00.
Choose Advanced NMN Powder
FAQ
Straight Answers Before You Buy.
What is Advanced NMN Powder?
Advanced NMN Powder is a RevGenetics 100-gram 99% pure NMN support powder designed for precision sublingual dosing. The protocol uses one flat level scoop of the included scoop, which provides about 400mg.
Why did you switch from 25-gram jars to 100-gram jars?
Same 99% pure NMN powder, now four times more per jar. The 100-gram jar gives daily users better value per gram, about 250 servings instead of 147, and far fewer reorders per year.
How do I take Advanced NMN Powder sublingually?
Take one flat level scoop, about 400mg, using the included scoop. Place the powder under your tongue, hold it there for 60-90 seconds without swallowing, then swallow the remaining residue and rinse with a small amount of water.
Do I need a milligram scale?
No. Each flat level scoop of the included scoop provides about 400mg, so everyday dosing needs no scale at all. A 0.001g milligram scale remains optional for advanced users who want a custom practitioner-guided dose.
How many servings are in the 100g jar?
The 100-gram jar contains 100,000mg total powder. At about 400mg per flat level scoop, that equals approximately 250 servings.
What is the cost per serving?
At the current storefront price of $110.00 and approximately 250 servings per jar, the cost is about $0.44 per 400mg serving.
Can I mix Advanced NMN Powder into water?
Do not mix it into water or beverages if you are trying to follow the sublingual protocol. Mixing it into a drink changes the method to oral swallowing and removes the direct under-the-tongue contact period.
How long should I hold the powder under my tongue?
Hold the measured powder under your tongue for 60-90 seconds, then swallow any remaining residue and rinse with water.
Why is powder more stable than liquid NMN?
The product education content explains that water exposure can trigger hydrolysis in liquid NMN solutions, while powder avoids that immediate water-driven degradation problem and supports longer shelf stability.
What does the clinical study summary say?
The current product education cites a randomized, double-blind, placebo-controlled study of 66 healthy adults aged 40-65, showing an 11.3% NAD+/NADH increase at day 30 and a 38% increase at day 60 with daily dosing. Individual results vary.
What is SLC12A8?
SLC12A8 is a transporter discussed in NMN precursor research and in the current product education content. The product positions sublingual use as a way to support faster delivery than swallowed capsule formats.
Can I take Advanced NMN Powder with resveratrol?
Many customers pair NAD+ support with resveratrol because sirtuins require NAD+ as a cofactor. Advanced NMN Powder can be paired with products such as M98 Resveratrol Complete, but add one supplement at a time and consult a healthcare provider if taking medication.
Who should not use Advanced NMN Powder without medical guidance?
Consult a healthcare provider before use if pregnant, nursing, under 18, taking medication, managing an illness, preparing for surgery, or under medical care for any condition.
What is the current storefront price?
The current storefront price for Advanced NMN Powder is $110.00.
Scientific References
- Yoshino M, et al. Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women. Science. 2021;372(6547):1224-1229. PubMed: 33888596.
- Igarashi M, et al. Chronic nicotinamide mononucleotide supplementation elevates blood nicotinamide adenine dinucleotide levels and alters muscle function in healthy older men. Referenced in the current product education with DOI: 10.3389/fragi.2022.851698.
- Grozio A, et al. Slc12a8 is a nicotinamide mononucleotide transporter. Nature Metabolism. 2019;1(1):47-57. PubMed: 31008510.
- Mills KF, et al. Long-term administration of nicotinamide mononucleotide mitigates age-associated physiological decline in mice. Cell Metabolism. 2016;24(6):795-806. PubMed: 28068222.
- Yoshino J, et al. Nicotinamide mononucleotide, a key NAD+ intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. Cell Metabolism. 2011;14(4):528-536. PubMed: 21982712.
Authored and formulated by Anthony Loera, Founder and CEO, RevGenetics. RevGenetics was founded on January 1, 2007 and has 19+ years of longevity supplement formulation experience as of 2026. Advanced NMN Powder has been manufactured under RevGenetics GMP standards since 2016 according to the current product education content.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Advanced NMN Powder is intended for general health support only. Individual results may vary. Consult your healthcare provider before use, especially if taking medications, pregnant, nursing, managing a medical condition, or under medical supervision.
Advanced NMN Powder RevGenetics NMN powder 100 gram NMN powder sublingual NMN powder NMN precursor powder 400mg NMN powder scoop flat level scoop NMN powder 30 minute absorption SLC12A8 NMN transporter NMN powder vs liquid NMN stability 99% pure NMN powder cellular energy support NAD+ support sirtuin support mitochondrial support healthy aging supplement NMN powder made in USA GMP RevGenetics founded 2007 19+ years 250 servings
🧬 Research Dosage Converter
Allometric scaling using FDA Km factors to compare doses across species
© RevGenetics Methodology 2025 (Protected ID: RG-CALC-20250907)
Equivalent Dosages
| Species | Equivalent Dose (mg/kg) | Total Amount / Day (mg) | Method |
|---|
Research reference only. Uses FDA Km factors: Human 37, Dog 20, Rat 6, Mouse 3. Estimated Km for Worm 1000, Fly 500. Conversion: DoseB = DoseA × (KmA / KmB). Total mg computed from assumed weights above. © 2025 RevGenetics, LLC. Unauthorized reproduction prohibited (ID: RG-CALC-20250907).
