Senolytic Supplements: Clear Zombie Cells
Two protocols for senescent cell clearance: Fisetin pulse dosing (5 days/month, 25-50x absorption) or Quercetin daily maintenance (85x absorption). Choose your senolytic strategy.
Understanding Senolytics and Zombie Cell Clearance
Senolytics are compounds that selectively eliminate senescent cells, commonly called "zombie cells." Cellular senescence (Wikidata Q2737127) occurs when damaged cells permanently stop dividing but refuse to die through normal apoptosis. Instead, these dysfunctional cells accumulate with age and secrete a toxic mix of inflammatory factors known as the Senescence-Associated Secretory Phenotype (SASP). This chronic inflammation damages surrounding healthy tissue and accelerates aging throughout the body.
RevGenetics offers two distinct senolytic approaches designed for different protocols and goals. Understanding the difference between pulse dosing and daily maintenance helps you select the right product for your needs.
What Are Zombie Cells?
Senescent "zombie" cells are damaged cells that have entered a permanent growth arrest but resist normal cell death. They consume resources, release inflammatory signals (IL-6, IL-8, TNF-alpha), and actively damage neighboring healthy cells. Research shows that clearing these cells can restore tissue function and reduce age-related inflammation. The challenge is that zombie cells have activated survival pathways that protect them from normal clearance mechanisms.
Super Fisetin 500 uses RGBooster1 patent-pending technology to achieve 25-50x better absorption than standard fisetin. This allows a 500mg dose to deliver efficacy equivalent to 1,400-2,000mg of standard fisetin (the dose range used in clinical trials like AFFIRM-LITE). Super Fisetin is designed for intensive pulse dosing: 5 consecutive days per month to trigger significant senescent cell clearance events.
MetaQuercetin SuperZ uses liquid micelle technology to achieve 85x better absorption than standard quercetin. This formula includes zinc ionophore activity for additional immune support. MetaQuercetin is designed for daily maintenance: consistent daily dosing to provide ongoing senolytic activity and prevent new senescent cell accumulation.
Why Absorption Technology Matters
Standard fisetin and quercetin have notoriously poor bioavailability, with only 1-17% of the compound reaching systemic circulation. Clinical trials require massive doses (1,400-2,000mg fisetin) to achieve therapeutic levels. RevGenetics developed proprietary absorption technologies to solve this fundamental limitation. RGBooster1 and liquid micelle delivery systems allow effective senolytic action at practical dose levels.
Choose Your Senolytic Protocol
Intensive clearance or daily maintenance?
Pulse Dosing Protocol
5 consecutive days per month for intensive senescent cell clearance. High-potency fisetin triggers significant apoptosis events.
Daily Maintenance Protocol
Consistent daily dosing for ongoing senolytic activity. Prevents new accumulation plus immune support benefits.
Senolytic Comparison Matrix
Fisetin (Pulse) vs Quercetin (Daily)
| Feature | Super Fisetin 500 | MetaQuercetin SuperZ |
|---|---|---|
| Active Compound | Fisetin 500mg | Quercetin (liquid micelle) |
| Absorption Technology | RGBooster1 (25-50x) | Liquid Micelle (85x) |
| Equivalent Standard Dose | 1,400-2,000mg fisetin | High-dose quercetin |
| Dosing Protocol | Pulse (5 days/month) | Daily maintenance |
| Primary Action | Intensive senescent cell clearance | Ongoing senolytic + immune |
| Additional Benefits | Potent antioxidant | Zinc ionophore (immune) |
| Format | Capsules | Liquid capsules |
| Supply Duration | 6 months | 1 month |
| Price | $222.20 (6-month) | $45.00 |
| Best For | Periodic intensive clearance | Daily senolytic maintenance |
Shop Senolytic Supplements
Super Fisetin 500
- 500mg fisetin with RGBooster1 (25-50x absorption)
- Equivalent to 1,400-2,000mg standard fisetin
- 5-day monthly pulse dosing protocol
- 6-month supply included
- Patent-pending delivery technology
MetaQuercetin SuperZ
- Liquid micelle quercetin (85x absorption)
- Zinc ionophore for immune support
- Daily senolytic maintenance protocol
- Nano-quercetin particles
- Liquid capsule format
Frequently Asked Questions
What are senolytics and what do they do?
Senolytics are compounds that selectively clear senescent "zombie" cells. These damaged cells stop dividing but refuse to die, accumulating with age and releasing inflammatory factors that damage surrounding tissue. Senolytics target the survival pathways keeping these cells alive.
What is the difference between fisetin and quercetin?
Fisetin is a more potent senolytic best used with pulse dosing (5 days/month) for intensive clearance. Quercetin provides daily senolytic maintenance plus immune support via zinc ionophore activity. Many protocols combine both for comprehensive coverage.
Why does absorption matter for senolytics?
Standard fisetin and quercetin have only 1-17% bioavailability. Clinical trials require 1,400-2,000mg fisetin for effect. RevGenetics developed RGBooster1 (25-50x) and liquid micelle (85x) technologies to achieve therapeutic levels at practical doses.
Should I use pulse dosing or daily dosing?
Pulse dosing (5 days monthly) with fisetin creates intensive clearance events. Daily dosing with quercetin provides ongoing maintenance and immune support. Many users combine both: Super Fisetin monthly plus MetaQuercetin daily.
Can I combine Super Fisetin and MetaQuercetin?
Yes. RevGenetics designed these products to work synergistically. Use Super Fisetin for 5 consecutive days per month and MetaQuercetin daily throughout the month for both intensive clearance and ongoing maintenance.
How long until I notice results?
Most users report improved energy and reduced inflammation within 2-4 weeks. Optimal results appear after 2-3 months as accumulated senescent cells are progressively cleared. Benefits include better energy, mental clarity, and reduced joint discomfort.
Important Health Information
FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Quality Assurance:
- GMP certified manufacturing
- Third-party laboratory tested
- Patent-pending delivery technology
- FDA registered facility
- Ships to 50+ countries