The age of the population is steadily growing throughout the world, and the need for anti-aging health products to ensure longevity and reduce problems associated with age is also increasing. Amid various health products for anti-aging, nicotinamide mononucleotide (NMN) is receiving attention from consumers and scientists.
Nicotinamide adenine dinucleotide
(NAD+) levels in the body decrease as we age and are connected with a decline in mitochondrial energy production and oxidative stress, cognitive impairment, DNA damage, and +Inflammageing. Yet, NMN, as the precursor to NAD +, can slow the process by increasing NAD + levels within the body. Various in vivo studies have demonstrated positive results for the therapeutic effects of various age-related ailments using NMN supplementation. One preclinical and one clinical study has been conducted to examine the safety risks of NMN administration. A few additional human clinical studies are currently being conducted. A massive quantity of NMN anti-aging drugs derived from NMN are available; appropriate research is required to assess the effectiveness and safety of NMN supplement.
As human lifespans continue to grow across the globe, so does the demand for solutions to age-related ailments. Nicotinamide Mononucleotide (NMN) is among the major precursors to nicotinamide adenine dinucleotide (NAD +), an enzyme essential to perform various cell-related functions such as metabolism and DNA repair, as well as cell expansion and longevity. Amazing results in animal and cell studies and research trials fuel the multimillion-dollar market of NMN supplements.
“In rodents, NMN supplement helps to counteract the harmful consequences associated with NAD + reduction as we age and significantly enhance various metabolism functions,” claims Samuel Klein, a doctor, and nutrition specialist at the Washington University School of Medicine in St Louis, United States. “This has resulted in NMN being widely sold as a diet supplement but with little evidence to show that it has beneficial effects for humans.”
Cosmetics and healthcare products containing NMN supplement are becoming more well-known across North America, Europe, and China. The world NMN market was worth $253 million in 2020 and is expected to grow to $386 million by the year 2027 end. 1.. But is there any evidence to support the claim that NMN is anti-aging in humans? This article examines studies published since 2015 that have examined the effects of NMN supplement on human metabolism and skin aging.