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Discussion of resveratrol and curcumin as Chemopreventative agents and Anticancer drug.

Discussion of resveratrol and curcumin as Chemopreventative agents and Anticancer drug.

anthony-loera anthony-loera
2 minute read

In October their were many exciting papers describing research on resveratrol. Two independent reviews discuss the combined use of resveratrol and curcumin as chemopreventative agents and anticancer drugs (Nutrition and Cancer Volume 62, Issue 7 October 2010, pp. 958-967 and Molecules 2010, 15, pp. 7035-7074). In Nutrition and Cancer, the authors discuss the importance of using natural compounds that can target carcinogenic pathways without adverse side effects. Resveratrol and curcumin were the compounds discussed in the article that was used as a method for preventing colorectal cancer. Targeting colorectal cancer is an appealing idea given the fact that it is the second cause of cancer death in the western culture but also because it is slow-developing cancer. The speed of progression from the adenoma stage to the carcinoma can take up to 10 years. This allows for a window of opportunity where treatments could destroy or further slow cancer. The second article in the journal Molecules reviews the mechanisms of how these two compounds might be working to slow or kill leukemic cells. This article mentions how these two compounds are currently being tested in clinical trials for their anticancer abilities. In addition, the paper discusses different resveratrol and curcumin analogous molecule's ability to antagonize cancer cells but also discusses the bioavailability of these compounds once ingested. [1][2]


  1. https://www.tandfonline.com/doi/abs/10.1080/01635581.2010.510259
  2. https://www.sciencedirect.com/science/article/abs/pii/S1044579X20302157

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