TA-65 Articles By Anthony / September 1, 2014 Share 92 Tweet Share 3 What TA-65 Data Shows It Is Dramatically Better?RevGenetics has been the top independent researcher of TA-65 products outside of TA Sciences themselves. Recently we were given access to exciting unpublished data that TA Sciences has been collecting behind the scenes.Like thousands of our friends, you may find yourself adding TA-65 to your regimen after reading this newsletter. Please do so by following this link to support our research. Without you supporting us, we would not be able to provide new data like that presented here:(Purchase TA-65 only from RevGenetics by Clicking here)Quick Summary Of This News:TA Sciences provides RevGenetics new dataData shows TA-65 bioavailability beat 98% CycloastragenolDr Valenzuela talks FDA Bioavailbility Benchmarks UsedValenzuela explains how similar products can be differentValenzuela charts TA-65 compared To CycloastragenolData shows TA-65 provides up to 50 fold more!Cost comparison change due to new data:TA-65 is more bioavailable than high cost 98% CycloastragenolTA-65 is 6.8 times cheaper than low cost 50% Cycloastragenol due to the increased 50 fold higher levelsPurchase from RevGenetics and be first to be informed on price drops, sales and new productsWhat data was provided to RevGenetics?We were given full access to previously unpublished human pharmacokinetic (PK) blood data by TA Sciences. Below Dr. Valenzuela provides a summary on why this PK data is so important.As president of RevGenetics, I am proud to be able to provide this information to our customers and friends who have trusted us to provide them our recommendations based on the latest scientific data.I also appreciate Noel Thomas Patton for providing his time and the data that has us so excited regarding on the best tested telomerase activator, called TA-65. RevGenetics Reviews The TA-65 Scientific Data From TA Sciences Commentary on Data by Hector Valenzuela, Ph.D.Hector Valenzuela, Ph.D. – Professor and researcher on small molecule gene research and discovery.Our initial tests: Here at RevGenetics, we strive in verifying the quality of our products as well as others that we recommend, with the objective of bringing the best product to our customers. To this end, we had TA-65 analyzed and determined its main ingredient and decided to promote this product.HPLC Chromatograph Used Identify components in mixtureAdditional data from TA Sciences: After meeting with TA Sciences, which owns the rights to TA-65, we were provided with additional studies and permission to show the great difference in effectiveness of various products bioavailability in comparison to TA-65 and we would like to share this information with our customers.First, however, we need to frame this information:Benchmarks used by the FDA: First, we must remember that the FDA does not regulate natural compounds as drugs, however, the benchmarks used by the FDA to compare drugs effectiveness are still very applicable for comparing natural compounds effectiveness. With this in mind, according to the FDA’s guidance for industry for orally administered drug products, bioavailability of a drug (in our case a natural compound) is defined as the rate and extend to which the active ingredient is absorbed from a drug product and becomes available at the site of action (Reference 1).In other words, a compound that is digested must get into the blood stream and then reach the target cells in your body to have a positive effect.If a compound does not reach the target cells that compound will be of no value. In this context then bioavailability then refers to the compounds ability to reach the target cells in meaningful concentrations.Determining meaningful concentrations: To determine concentrations, compounds in the serum can be measured by drawing blood from an individual. There are three parameters that you want to keep in mind when looking at studies of this nature. First, how high is the peak blood serum level, what was the time-to-peak blood serum level and finally, what is the area under the curve?You may ask yourself what does this all mean?Keeping it simple: In essence these are indicators of bioavailability, if larger amounts of the compound survives your digestive track and gets into your bloodstream, then it is more likely that a smaller amount of the compound will be required to have a desirable effect and the effect may be for a longer period of time.Why similar products can be quite different: How can similar compounds have different bioavailability effects? There are various methods to increase the delivery effectiveness of a compound. Most revolve around adding additional compounds that modify and increase the effectiveness. This appears to be the case for TA-65. The following graph illustrates various cycloastragenol containing compounds bioavailability in the serum. It is quite obvious from the graph that TA-65 reaches the highest levels of cycloastragenol in the serum.TA-65 vs Cycloastragenol In Human VolunteersTA-65 Serum Levels Dramatically Better:Furthermore, two hours after consumption, TA-65 clearly had higher serum levels than the other compounds and peaked after five hours. Finally, the area under the graph represents the collective amount of cycloastragenol found in the serum, which was far greater than the other compounds.Dramatically better: What makes the results more dramatic is that the capsules of TA-65 contain less cycloastragenol than the 50 mg 98% pure cycloastragenol and yet is accounts for a much higher amount of cycloastragenol in the serum. The calculated area under the curve indicates that TA-65 had 50 fold higher levels of cycloastragenol in the blood serum than the 50% pure cycloastragenol capsules.Summary of data: In summary, although all the compared compounds contain cycloastragenol that could be detected in the serum, it is clear that TA-65 had the highest levels of cycloastragenol. The unique formulation of TA-65 appears to allow for a larger amount of cycloastragenol to reach the blood stream and therefore more likely exert its positive effects on its target cells. The reason we believe the formulation has been successful is because TA Sciences has spent over 10 years focused on developing and improving the bioavailability of TA-65.We hope that this new data will help clarify any questions about our recommended TA-65 products.More to come… In our next newsletter we will provide the list of studies on TA-65 that have provided us exciting reasons to fully recommend TA-65 as our best and only telomerase activator.Cost Comparisons Regarding TA-65 Further Commentary by Anthony Loera, President of RevGeneticsAfter reviewing the new TA Sciences data with our Chief Science Officer, It dawned on me why TA-65 was easily the preferred product over the others.From a purity and bioavailability standpoint: 50mg of 98% pure material as shown in the chart, would be less bioavailable than 16mg of TA-65 with it’s unique formulation.From a cost perspective: Even using the cheap 50% material (which is the cheaper raw material on the market) will not stack up to TA-65.A typical person would likely need to purchase $1500 of a 50% Cycloastragenol product sold at about $30 a bottle (Yes…you would need to buy 50 bottles!)… to come close to what a single $219 (30 capsule) bottle of TA-65 would provide (from a bioavailability standpoint as shown on the chart).Why we recommend TA-65: Using the new data we believe that… Hands down, TA-65 is simply the best tested telomerase activator we have researched. We firmly believe it to be the leader simply because of it’s proven bioavailability over high purity material, telomerase activation, ongoing studies and comparative low cost.Like thousands of our friends, you may find yourself adding TA-65 to your regimen after reading this newsletter. Please do so by following this link to support our research. Without you supporting us, we would not be able to provide new data like that presented here:(Purchase TA-65 only from RevGenetics by Clicking here) TA-65 Data Shows It Is Dramatically Better Reviewed by Dr. Hector F. Valenzuela on Sep 1 Rating: 5.0 New TA-65 Data Shows It Is Dramatically Better Data shows TA-65 is up to 50x better than previously believed. Read about the dramatically better TA-65 human volunteer data provided to RevGenetics and scientist reviewed.