Not Just Green Tea Extract. EGCG Built to Get Past the Absorption Barrier.
RevGenetics EGCG 800 delivers 800mg of 98% pure caffeine-free EGCG from green tea extract, enhanced with RGBooster1 to help address the P-glycoprotein efflux problem that limits standard EGCG absorption.*
If Your Green Tea Extract Is Not Working, It May Be the P-gp Problem.
EGCG is one of the most studied green tea polyphenols, but standard EGCG has a major delivery problem. P-glycoprotein efflux pumps in the intestinal lining can move EGCG back into the gut after it enters intestinal cells, reducing how much reaches circulation.
EGCG 800 is designed around that problem. It combines a clinical-strength 800mg serving of 98% pure EGCG with RGBooster1, a patent-pending P-glycoprotein efflux modulator, without caffeine.*
- 800mg EGCG per serving from premium Camellia sinensis green tea leaf extract.
- 98% pure EGCG yielding approximately 784mg of pure Epigallocatechin-3-gallate per serving.
- 0mg caffeine for people who want green tea polyphenol support without jitters, anxiety, palpitations, or sleep disruption.
- RGBooster1 absorption technology designed to modulate P-glycoprotein efflux pumps at the intestinal barrier.*
- 80-cup green tea equivalent based on approximate EGCG content from brewed green tea, without the caffeine burden.*
- Third-party tested, Non-GMO, vegan, GMP-compliant, and made in the USA.
Important Safety Notice
Do not use if pregnant, nursing, or under 18 years of age. If you have a medical condition, liver disorder, or take prescription medications, consult your physician before use. Take with food for best tolerance. Do not exceed 2 capsules, equal to 800mg EGCG, per day.
Discontinue use and consult a physician if you experience nausea, abdominal pain, dark urine, or yellowing of the skin or eyes.
Cups of Green Tea Polyphenol Equivalent
One cup of green tea contains roughly 50mg of EGCG. EGCG 800 provides a concentrated 800mg serving of 98% pure EGCG in 2 caffeine-free capsules.*
A Clinical Dose Without the Caffeine Load.
Achieving high EGCG intake through brewed green tea would require drinking large amounts of tea, along with substantial caffeine. EGCG 800 removes the stimulant burden while keeping the polyphenol target high.
That makes it a cleaner option for caffeine-sensitive users, fasting protocols, and longevity stacks where you want the green tea catechin without nervous-system stimulation.*
What Is RevGenetics EGCG 800?
RevGenetics EGCG 800 is a caffeine-free green tea extract supplement that delivers 800mg of 98% pure Epigallocatechin gallate per serving. It uses RGBooster1, a patent-pending P-glycoprotein efflux modulation technology, to support EGCG absorption and is designed for cellular health, antioxidant pathway support, metabolic function, Nrf2 activation, AMPK pathway support, and healthy aging routines.*
What it is
A high-potency caffeine-free EGCG supplement from Camellia sinensis green tea leaf extract.
Who it is for
Adults who want green tea polyphenol support without caffeine, jitteriness, or sleep disruption.
How to take it
Take 2 capsules daily with food. Space at least 2 hours away from iron-rich meals or iron supplements.
Key Specifications
| Specification | RevGenetics EGCG 800 |
|---|---|
| Active compound | Epigallocatechin-3-gallate, EGCG, C22H18O11 |
| Dose per serving | 800mg green tea extract standardized to 98% pure EGCG |
| Approximate pure EGCG yield | 784mg pure EGCG per serving |
| Caffeine | 0mg, completely caffeine-free |
| Absorption technology | RGBooster1, patent-pending P-glycoprotein efflux modulation technology |
| Botanical source | Camellia sinensis green tea leaf extract |
| Servings per container | 30 servings, 60 capsules |
| Certifications and quality | Non-GMO, vegan, GMP-compliant, made in USA, independent third-party tested |
| Suggested use | Take 2 capsules daily with food. Do not exceed 2 capsules per day. |
| Current storefront price | $62.26 |
P-gp Modulation Potency Compared With Piperine at This Mechanism
The current product record describes RGBooster1 as acting at the P-glycoprotein efflux pump level at 300x the potency of standard piperine at this specific mechanism.*
Standard EGCG bioavailability range cited in the current product text.
Approximate circulating EGCG from a typical 800mg capsule at low standard bioavailability.
Caffeine per serving.
EGCG 800 Is Not a Standard Green Tea Pill.
EGCG 800 is a precision-engineered green tea polyphenol formula that addresses the three major barriers that prevent EGCG from working at meaningful concentrations: dose, efflux, and caffeine burden.*
Layer 1: The Clinical Dose
Each serving starts with 800mg of green tea extract standardized to 98% EGCG, yielding approximately 784mg of pure EGCG per serving.*
Layer 2: The Absorption Engine
RGBooster1 is designed to modulate intestinal P-glycoprotein efflux pumps, helping more EGCG move toward systemic circulation instead of being pushed back into the gut.*
Layer 3: Stimulant-Free Formula
EGCG 800 is rigorously decaffeinated, allowing a high EGCG dose without caffeine-driven jitters, anxiety, heart palpitations, or sleep disruption.
Built for People Who Want Green Tea Polyphenols Without the Weaknesses of Green Tea.
Biohackers and Longevity Enthusiasts
For people targeting cellular senescence, autophagy, AMPK, Nrf2, and cellular aging pathway support at meaningful concentrations.*
Intermittent Fasting Protocol Users
A caffeine-free green tea polyphenol option for metabolic pathway routines during fasting-focused schedules.*
Caffeine-Sensitive Individuals
For people who want green tea’s polyphenol benefits without CNS stimulation, jitters, anxiety, or sleep disruption.
Anti-Aging Stack Builders
A foundational polyphenol option to pair with NMN, resveratrol, quercetin, fisetin, or other longevity routines.*
Users Disappointed by Standard Extracts
For people who tried low-dose, non-standardized, or poorly absorbed green tea supplements with minimal results.
First-Time EGCG Buyers
For buyers who want a clean-label, caffeine-free, high-potency EGCG product with third-party testing.
Six Targeted Benefits.
Autophagy Activation*
Preclinical research suggests EGCG may activate autophagy pathways by modulating the AMPK and mTOR axis, key switches involved in cellular cleanup processes.
Cellular Senescence Support*
Preclinical research indicates EGCG may modulate pathways associated with cellular senescence and SASP, the senescence-associated secretory phenotype.
Nrf2 Pathway and Antioxidant Defense*
EGCG has been studied for activation of the Nrf2/Keap1/P62 pathway, which is connected to endogenous antioxidant defense systems.
Metabolic Support and Fat Oxidation*
Clinical research shows green tea catechins can support fat oxidation during moderate exercise and may support healthy metabolic parameters.
Cardiovascular Health Support*
Green tea catechins are associated with endothelial health markers and vascular support in peer-reviewed clinical literature.
Cognitive Support*
EGCG has been studied in laboratory and animal models for brain-related effects, while human studies support green tea consumption for cognitive function in older adults.
Why Standard EGCG Often Underperforms.
P-glycoprotein efflux pumps are transporter proteins found in the intestinal lining. After EGCG enters intestinal cells, these pumps can move it back toward the gut lumen before it reaches systemic circulation.
Most absorption enhancers focus later in the process. Piperine, for example, is often used for CYP3A4 inhibition after absorption. RGBooster1 is designed to work earlier, directly at the P-gp efflux pump level, where EGCG loss is a major barrier.*
EGCG 800 vs. Standard Green Tea Pills vs. Brewed Green Tea
| Feature | RevGenetics EGCG 800 | Standard Green Tea Pills | Brewed Green Tea |
|---|---|---|---|
| EGCG per serving | 800mg, 98% pure | Often 100-200mg, commonly 40-50% purity | About 50mg per cup |
| Caffeine | 0mg, caffeine-free | Naturally occurring unless removed | About 35-50mg per cup |
| Absorption technology | RGBooster1 P-gp modulation technology* | Usually none | None |
| Standard bioavailability problem | Designed to address P-gp efflux* | 0.1-1.68% cited standard range | 0.1-1.68% cited standard range |
| Quality testing | Independent third-party tested | Varies by brand | Not applicable |
| Best fit | High-potency, caffeine-free, targeted EGCG routine | General green tea supplement use | Traditional beverage use |
Simple, Safe, Consistent Use.
Take 2 Capsules Daily
Take 2 capsules per day for a full 800mg serving. Do not exceed 2 capsules daily.
Take With Food
Take with a meal for better stomach comfort and consistent absorption.
Use Morning or Early Afternoon
Morning or early afternoon is preferred for routine consistency, even though the formula has 0mg caffeine.
Space Away From Iron
Take at least 2 hours apart from iron-rich meals or iron supplements because EGCG can bind iron.
Iron and Liver Safety Notes
EGCG is a natural iron chelator. This can be useful in certain research contexts, but it may interfere with iron absorption. Space EGCG 800 at least 2 hours away from iron supplements or iron-rich meals. If you have anemia, consult your physician before use.
If you have a history of liver conditions, consult your physician before using concentrated green tea extract. Discontinue use and seek medical guidance if you experience nausea, abdominal pain, dark urine, or yellowing of the skin or eyes.
Cellular Pathways, Not Stimulant Effects.
EGCG 800 works through cellular and enzymatic pathways, not caffeine-driven stimulation. Results build with consistent daily use and should not be judged like a stimulant or pre-workout product.
Weeks 4-8*
Initial support for metabolic pathways, antioxidant defense, and Nrf2 pathway engagement may become more noticeable with consistent use.
Days 60-90*
Deeper cellular aging support may involve autophagy support and senescence pathway modulation over longer, consistent use.
No Caffeine Spike
EGCG 800 is not designed to create a stimulant rush. It is a caffeine-free cellular health supplement.
This is a cellular health supplement, not a medication. It does not replace prescribed treatment. Consult your healthcare provider with questions about your personal health.
A Foundational Polyphenol for Cellular Health Routines.
EGCG 800 can be used as a standalone product or as part of a broader longevity stack. It pairs naturally with NAD+ support, sirtuin support, and cellular renewal routines.*
EGCG + NMN + Resveratrol*
Combines EGCG’s Nrf2 and polyphenol pathway support with NAD+ production and sirtuin-focused routines.
EGCG + Quercetin or Fisetin*
Adds complementary senescence and cellular housekeeping support for advanced renewal routines.
Stack Carefully
High-dose botanical combinations have limited human trial data. Add one product at a time and consult your healthcare provider.
Real-World Feedback.
Reviews reflect individual customer experiences. Individual results may vary.
“I wanted the longevity benefits of EGCG but I am incredibly sensitive to caffeine. This formula has been perfect. I take it every morning with breakfast and I can feel the difference in my energy and focus.”Michael T., Verified Buyer
“After reading the research on autophagy and cellular aging, I added this to my fasting protocol. The quality is exceptional and I trust RevGenetics' independent third-party testing.”Sarah L., Verified Buyer
“A staple in my anti-aging stack. You literally cannot drink enough green tea to match what is in two of these capsules, without spending all day on caffeine.”David R., Verified Buyer
A Better EGCG Formula Starts With the Absorption Problem.
“We did not just want to create another green tea extract. We wanted to provide the concentrated polyphenol dose used in longevity research, without the jitters. For more than 19 years, RevGenetics has focused on the formulation problems most supplement companies ignore. EGCG 800 pairs 98% pure caffeine-free EGCG with RGBooster1 to help address P-gp efflux and support healthy cellular aging routines.”
Anthony Loera, Founder and CEO, RevGenetics. Miami, FL.
Built Around Testing, Formulation, and 19+ Years of Experience.
RevGenetics was founded on January 1, 2007. As of May 4, 2026, that equals more than 19 years of longevity supplement formulation experience.
EGCG 800 is authored and formulated by Anthony Loera, Founder and CEO of RevGenetics, and uses patent-pending RGBooster1 technology designed to address EGCG’s bioavailability problem. Every batch is independently third-party tested for purity, heavy metals, and verified catechin content before it ships.
- Independent third-party tested.
- Manufactured in a GMP-certified facility.
- Patent-pending RGBooster1 technology, USPTO application pending.
- Made in the USA.
- Non-GMO and vegan.
- Last reviewed: March 2026. Next review: September 2026.
Stop Wasting Money on EGCG Your Body Can Barely Absorb.
Get clinical-dose EGCG with RGBooster1 P-gp modulation, zero caffeine, third-party testing, and a 30-day guarantee.*
Current storefront price: $62.26.
Choose EGCG 800Straight Answers Before You Buy.
What is EGCG 800?
EGCG 800 is a high-potency caffeine-free green tea extract supplement delivering 800mg of 98% pure Epigallocatechin gallate per serving. It is enhanced with RGBooster1 technology to support EGCG absorption and cellular health routines.*
Does EGCG 800 contain caffeine?
No. EGCG 800 is completely caffeine-free, with 0mg caffeine per serving. You get green tea polyphenol support without jitters, palpitations, anxiety, or sleep disruption.
How does RGBooster1 work?
RGBooster1 is a patent-pending flavonoid complex designed to modulate P-glycoprotein efflux pumps in the intestinal lining. These pumps can move absorbed EGCG back out of intestinal cells. RGBooster1 is designed to reduce that efflux barrier so more EGCG can reach systemic circulation.*
When should I take EGCG 800?
Take 2 capsules daily with food. Morning or early afternoon is preferred for routine consistency. Space at least 2 hours away from iron supplements or iron-rich meals.
What makes EGCG 800 different from drinking green tea?
Brewed green tea contains much lower EGCG per serving and also contains caffeine. To reach 800mg EGCG through tea, you would need a very large amount of brewed green tea and would consume substantial caffeine. EGCG 800 provides the dose in 2 caffeine-free capsules with RGBooster1 absorption support.*
Does EGCG support autophagy?
Preclinical research suggests EGCG may activate autophagy pathways in laboratory and animal models by modulating AMPK and mTOR, which are involved in cellular cleanup. Human clinical evidence on direct autophagy activation is still emerging.*
Is EGCG 800 safe? Are there liver warnings?
EGCG 800 is intended for healthy adults when taken as directed. Do not exceed 800mg per day. If you have a history of liver conditions or take prescription medications, consult your physician before use. Discontinue and consult a physician if you experience nausea, abdominal pain, dark urine, or yellowing of the skin or eyes.
Can I stack EGCG 800 with other supplements?
EGCG 800 can be stacked with NMN and resveratrol for longevity routines. It may also be combined with quercetin or fisetin in advanced cellular renewal stacks, but high-dose botanical combinations should be discussed with your healthcare provider first.*
Can I take EGCG with iron supplements?
Space EGCG 800 at least 2 hours away from iron-rich meals or iron supplements. EGCG naturally chelates iron, which may reduce iron absorption. If you have anemia, consult your physician before use.
How long until I see results?
Many users look for foundational metabolic and antioxidant support over 4 to 8 weeks. Deeper cellular aging support, including autophagy and Nrf2 pathway engagement, is usually considered over 60 to 90 days of consistent daily use. Individual results vary.*
Is EGCG 800 vegan and non-GMO?
Yes. EGCG 800 is vegan, uses HPMC vegetable capsules, is Non-GMO, and is free from artificial additives, binders, and flow agents.
What is AMPK and does EGCG activate it?
AMPK, or AMP-activated protein kinase, is the body’s cellular energy sensor. In laboratory and animal models, EGCG has been shown to activate AMPK, a key pathway for metabolic efficiency and cellular energy balance. Human evidence is still being studied.*
Scientific References
- Venables MC, et al. Green tea extract ingestion, fat oxidation, and glucose tolerance in healthy humans. American Journal of Clinical Nutrition. 2008;87(3):778-784. DOI: 10.1093/ajcn/87.3.778.
- Ide K, et al. Effects of green tea consumption on cognitive dysfunction in the elderly. Nutrients. 2014;6(10):4032-4042. DOI: 10.3390/nu6104032.
- Singh BN, et al. Green tea catechin, epigallocatechin-3-gallate, EGCG: mechanisms, perspectives and clinical applications. Biochemical Pharmacology. 2011;82(12):1807-1821. DOI: 10.1016/j.bcp.2011.07.093.
- Hodgson AB, et al. The effect of green tea extract on fat oxidation at rest and during exercise. Advances in Nutrition. 2013;4(2):129-140. DOI: 10.3945/an.112.003269.
- Ullmann U, et al. Epigallocatechin gallate, EGCG, does not impair nonhaem-iron absorption in man. Phytomedicine. 2005;12(6-7):410-415. DOI: 10.1016/j.phymed.2004.07.001.
- López-Otín C, et al. The Hallmarks of Aging. Cell. 2013;153(6):1194-1217. DOI: 10.1016/j.cell.2013.05.039.
- Holczer M, et al. Epigallocatechin-3-Gallate, EGCG, promotes autophagy-dependent survival via influencing the balance of mTOR-AMPK pathways. Oxidative Medicine and Cellular Longevity. 2018. DOI: 10.1155/2018/6721530.
- Hao Y, et al. EGCG activates Keap1/P62/Nrf2 pathway, inhibits iron deposition and apoptosis. Scientific Reports. 2024;14. DOI: 10.1038/s41598-024-82938-y.
- Zhuang Z, et al. Comprehensive review of EGCG modification: esterification methods and their impact on bioavailability and efficacy. Foods. 2024;13(8):1232. DOI: 10.3390/foods13081232.
Authored and formulated by Anthony Loera, Founder and CEO, RevGenetics. RevGenetics was founded on January 1, 2007 and has 19+ years of longevity supplement formulation experience as of 2026.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. Consult with a qualified healthcare provider before starting any new supplement regimen.
