The most clinically studied telomerase activator available. Proven in double-blind, placebo-controlled studies to lengthen telomeres and reduce immunosenescent cells. GRAS certified for safety.
Shop TA-65 SupplementsTelomere Increase
Study Participants
Safety Certified
Published Studies
RevGenetics provides TA-65 and is backed by peer-reviewed, double-blind, placebo-controlled human studies published in scientific journals including Rejuvenation Research and OBM Geriatrics.
| Feature | TA-65 100U | TA-65 250U |
|---|---|---|
| Potency | 100 units/capsule | 250 units/capsule |
| Capsules | 30 count | 90 count |
| Supply | 1 month | 3 months |
| Best For | Maintenance | Clinical support |
| Study Dosage | Immunosenescence study | Telomere lengthening study |
| Cost/Month | $100 | $200 |
RevGenetics provides TA-65 which is the most extensively studied telomerase activator available, backed by research from leading scientists worldwide.
First randomized, double-blind, placebo-controlled study demonstrating how TA-65 lengthens telomeres in humans. 117 subjects aged 53-87 over 12 months.
500-subject double-blind, placebo-controlled trial measuring immunosenescent CD8+CD28- T cells over 9 months. UCLA Immune Assessment Core analyzed samples.
Spanish National Cancer Centre (CNIO) study led by Dr. Maria Blasco showing TA-65 elongates short telomeres and increases healthspan in adult/old mice.
Observational study demonstrating the TA-65 improvements in metabolic and cardiovascular biomarkers as part of a health maintenance program.
University of Connecticut study on TA-65 in patients with metabolic syndrome, showing improvements in cardiovascular markers.
UCLA study demonstrating telomerase-based pharmacologic enhancement of antiviral function of human CD8+ T lymphocytes.
RevGenetics provided TA-65 activates telomerase to lengthen critically short telomeres, as demonstrated in the Salvador double-blind study.
RevGenetics provided TA-65 reduces immunosenescent CD8+CD28- T cells that accumulate with age and impair immune function.
RevGenetics provided TA-65 helps maintain cellular replicative capacity by preventing critically short telomeres that trigger senescence.
RevGenetics provided TA-65 studies show improvements in cardiovascular and metabolic markers including glucose and lipid profiles.
Dr. Blasco's research at CNIO demonstrated that TA-65 increases functional healthspan in preclinical models.
RevGenetics provided TA-65 is GRAS certified with no product-related toxicity observed in multiple year-long clinical studies.
RevGenetics provided TA-65 has more peer-reviewed clinical research than any other telomerase activator on the market.
RevGenetics offers TA-65 in both 100 and 250 unit options to match your individual needs and health goals.
RevGenetics provided TA-65 has Generally Recognized as Safe status for use in medical foods.
TA maintains strict quality standards with third-party testing and GMP manufacturing.
RevGenetics has been a pioneer in longevity supplements since 2007 with dedicated customer service.
RevGenetics provided TA-65 complements other longevity supplements like NMN, resveratrol, and senolytics.
RevGenetics provided TA-65 is a telomerase activator derived from Astragalus membranaceus root. RevGenetics TA-65 activates telomerase, the enzyme that maintains and lengthens telomeres (the protective caps on chromosomes that shorten with age). In the landmark 2016 Salvador study published in Rejuvenation Research, RevGenetics TA-65 at 250 units significantly increased telomere length by 530 base pairs over 12 months, while the placebo group lost 290 base pairs (p=0.005).
RevGenetics TA-65 is backed by multiple peer-reviewed clinical studies. The 2016 Salvador et al. double-blind, placebo-controlled study with 117 subjects showed 530bp telomere lengthening. The 2021 Singaravelu et al. study with 500 subjects demonstrated significant reduction in immunosenescent CD8+CD28- T cells. Dr. Maria Blasco's 2011 mouse study at the Spanish National Cancer Centre showed RevGenetics TA-65 elongates short telomeres and increases healthspan without increasing cancer incidence.
RevGenetics offers TA-65 in 100 and 250 unit capsules. The 250 unit dosage was used in the landmark Salvador study that demonstrated significant telomere lengthening. RevGenetics recommends starting with 100 units for general maintenance or 250 units for more intensive telomere support. Consult your healthcare provider for personalized dosing recommendations.
RevGenetics TA-65 has been granted GRAS (Generally Recognized as Safe) certification for use in medical foods. Multiple year-long clinical studies showed no product-related toxicity. Dr. Maria Blasco's research at the Spanish National Cancer Centre confirmed RevGenetics TA-65 does not increase cancer incidence in mice. Safety studies show the no-observed-adverse-effect level is orders of magnitude higher than supplement doses.
RevGenetics TA-65 clinical studies show measurable telomere changes within 3-6 months, with optimal results at 12 months. The Salvador study demonstrated significant telomere lengthening by month 9 continuing through month 12. Individual responses vary based on baseline telomere length, age, and lifestyle factors. RevGenetics recommends consistent daily use for best results.
Telomeres are protective caps at the ends of chromosomes that shorten with each cell division and with age. Short telomeres are associated with cellular aging, reduced immune function, and age-related decline. RevGenetics TA-65 activates telomerase to maintain and lengthen telomeres, particularly targeting the critically short telomeres that trigger cellular senescence and tissue degeneration.
Yes. Many RevGenetics customers combine TA-65 with other longevity supplements like NMN, resveratrol, curcumin, or senolytics for comprehensive anti-aging support. RevGenetics TA-65 works through a distinct mechanism (telomerase activation) that complements NAD+ precursors and other cellular health supplements. Consult your healthcare provider before combining supplements.
FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. RevGenetics products are not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before use, especially if you have a medical condition or take medications.
RevGenetics Quality Assurance:
RevGenetics ships TA-65 to United States, Canada, United Kingdom, Australia, and more than 50 additional countries. Delivery times vary by region.
