Telomerase treatment in a lab extends lifespan:
In May 15th, the Journal for Molecular Medicine published a new telomerase treatment study by Maria Blasco and Bruno Bernardes. The researchers at the Spanish National Cancer Research Centre, had realized that telomerase in our cells could hold the key to a better lifespan with a decreased incidence of diseases. This prompted them to see if they could actually test this theory by using gene therapy, instead of altering the animals genes permanently from a point earlier than birth.
Up until this time, it was unthinkable that older animals could be altered or treated as it has been very difficult to introduce telomerase into the genes, other than activating it using something like the TA-65 product that Blasco tested in 2011.
In Blasco's latest published study, Blasco's team cleverly used a DNA-modified virus that had it's viral genes replaced by the telomerase enzyme. The virus was then introduced to the animals, and the virus started repairing the old mice telomeres, slowing the mouses biological clock and consequently increased it's lifespan.
This was the first a known use of telomerase in a gene therapy that actually repaired the animal's DNA and allowed it to extend it's lifespan. This proof of concept study shows the power of telomerase to repair cells to where not only provides health benefits, but increases lifespan. This breakthrough study and it's researchers conclude that this study shows that it is feasible to use telomerase to extend lifespan, and the feasibility of gene therapy to help do it in one treatment.
At this time, this proof of concept treatment is impressive. Until the medical community and the FDA consider any new drugs based on this breakthrough study, we suggest taking the TA-65 supplement that Blasco also tested in 2011, and was shown to activate telomerase safely. TA-65 is available here (Buy TA-65)
- Bruno Bernardes de Jesus, Elsa Vera, Kerstin Schneeberger, Agueda M Tejera, Eduard Ayuso, Fatima Bosch, Maria A. Blasco. Telomerase gene therapy in adult and old mice delays ageing and increases longevity without increasing cancer. EMBO Molecular Medicine, 2012 (in press) DOI: 10.1002/emmm.201200245