Telomeres and Muscular Dystrophy – RevGenetics

Telomeres and Muscular Dystrophy

Telomeres and Muscular Dystrophy?

Duchenne muscular dystrophy, or DMD, is a diseased caused by a defective dystrophin gene needed for proper muscle structure and function. DMD is the most common childhood inherited muscular dystrophy, which affects approximately one in every 3500 male boys in the world. Although early symptoms can be observed in the deterioration of calf muscles and other lower limb muscles, it is the muscles involved in respiration and muscles of the heart that normally claim the life of those afflicted. Scientist that study DMD use a DMD rodent model, were the dystrophin gene is also mutated and nonfunctional. However…

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